What Is Ozempic Face?

In recent years, the use of GLP-1 agonists such as Ozempic, Mounjaro, and Saxenda has become increasingly common in weight control and obesity treatment. These medications promote rapid and effective weight loss by suppressing appetite and slowing gastric emptying.

However, this rapid weight loss can lead to noticeable changes in facial anatomy, just as it does in other parts of the body. This condition is now commonly referred to in both the literature and clinical practice as Ozempic Face.

Is Ozempic Face a Side Effect?

Contrary to popular belief, Ozempic Face is not a direct side effect of the medication.
It is a reflection of rapid weight loss on facial anatomy.

The face is a complex, multilayered structure composed of bone, muscles, connective tissue (SMAS), and fat compartments. During rapid weight loss, both deep and superficial facial fat compartments lose volume quickly.

As a result:

• The cheeks become hollow
• The temporal region loses volume
• The under-eye and midface areas appear sunken
• The face takes on a tired, fatigued, and unhealthy appearance

Why Is the Face More Affected by Rapid Weight Loss?

Compared to the rest of the body, the face has limited and delicate fat reserves.
Therefore, facial tissues struggle to adapt during rapid weight loss.

The most affected areas include:

• Midface fat pads
• Nasolabial region
• Temporal (temple) area
• Jawline and lower face

How Can Ozempic Face Be Prevented?

One of the fundamental principles of medicine applies here as well:
 “Prevention is better than treatment.”

The most effective preventive measures include:

• Gradual and controlled weight loss
• Avoiding sudden and excessive weight reduction
• Regular clinical evaluation of facial volume

This approach allows facial tissues to adapt and reduces the risk of permanent deformity.

Once facial changes have occurred, a standardized treatment approach is not appropriate.
Treatment must be individualized based on facial anatomy, age, and tissue quality.

We evaluate this process surgically in two main stages:

Stage 1: Volume Loss Without Significant Sagging

These patients present with:

• Noticeable facial volume loss
• Hollowing of the cheeks and midface
• No significant skin laxity yet

Fat Grafting is the most effective treatment option.
Autologous fat harvested from the patient is transferred to areas of volume loss using micro-injection techniques.

With proper planning:

• Facial fullness is restored
• The tired appearance improves
• Results are natural and long-lasting

At this stage:

• Fat compartments are significantly depleted
• Facial tissues have descended
• Skin elasticity is reduced

In these patients, volume restoration alone is insufficient.
 The primary issue is the loss of anatomical support.

The most effective solution:

Deep Plane Facelift

This advanced surgical technique:

• Does not rely on skin tightening alone
• Releases the SMAS and muscular layers
• Repositions tissues in their natural anatomical plane

As a result:

• The midface is naturally elevated
• The jawline is redefined
• Neck and lower face contours improve
• An artificial or over tightened appearance is avoided
• Results are durable and harmonious

Ozempic Face is a natural consequence of modern weight loss methods.
When addressed at the right time, using the correct techniques and respecting facial anatomy, it is:

• Preventable
• Reversible
• Correctable with natural and long-lasting results

Every face is unique.
 Therefore, the most effective treatment is always a personalized treatment plan.